47 results
Thrombotic Microangiopathies In Systemic Lupus Erythematosus

Dr. Laurent ARNAUD @Lupusreference

#TMAs #Thrombotic #Microangiopathies #Systemic #Lupus #Erythematosus #SLE #hematology
Microangiopathies In Systemic Lupus ... Microangiopathies #Systemic #Lupus ... Erythematosus #SLE ... #hematology #rheumatology ... differential #diagnosis #causes
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
vs SLE Drug Induced ... cases, drug-dependent ... • Immunologic Workup ... Discontinuation of causal ... • Immunologic Workup
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... , oral ulcers, Lupus ... • Immunologic Workup ... Positive in 60-80% of cases ... #lupus #Systemic
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
Measurement in SLE ... • Special cases ... (e.g. renal failure ... #Measurement #SLE ... pharmacology #levels #lupus
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Causes of Thrombocytopenia ... Diagnosis and Workup ... practices that could cause ... test, ANA (e.g., SLE ... #Workup #hematology
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
maintained fever CAUSES ... #Differential #Causes ... #Anesthesiology ... #Anesthesia #Checklist ... Diagnosis #Management #Workup
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... S - Systemic Lupus ... Erythematosus (total 50, renal ... #differential #hematology
Malignant Hyperthermia Crisis - Guidelines for Crises in Anaesthesia
Unexplained increase in ETCO2 AND tachycardia AND increased
other, more common causes ... ); may require renal ... Hyperthermia #Crisis #Anesthesiology ... Intraoperative #Checklist ... Diagnosis #Management #Workup
Hypotension - Guidelines for Crises in Anaesthesia

Hypotension is commonly due to unnecessarily deep anaesthesia, the autonomic
pressure as a cause ... o Endocrine cause ... #Differential #Anesthesiology ... Intraoperative #Checklist ... Diagnosis #Management #Workup
Cardiac Tamponade - Guidelines for Crises in Anaesthesia
Caused by an accumulation of blood, pus, effusion fluid
of underlying cause ... small volume may cause ... Cardiac #Tamponade #Anesthesiology ... Intraoperative #Checklist ... Diagnosis #Management #Workup