11 results
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... erythematosus ( ... erythematosus ( ... @AnnKumfer #Antinuclear ... rheumatology #diagnosis #differential
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... assay (IFA) is the main ... erythematosus ( ... @AnnKumfer #Antinuclear ... rheumatology #diagnosis #differential
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Associated with Joint Pain ... lesions • Discoid lupus ... erythematosus ... #dermatology ... #rashes #differential
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... findings (ANA, ... alopecia Differential ... Arthritis: • Joint pain ... Serositis Labs: • ANA
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
Inflammatory joint pain ... fingers, or pain ... the face (many differential ... #diagnosis #sle ... clues #system #erythematosus
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
XR, MRI to dx and ... dz difficult to see ... • Differentiate ... • Hematogenous ... diagnosis #causes #hematology
Aortitis - Differential Diagnosis Framework
Non-Infectious Aortitis:
 • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Aortitis - Differential ... Polyarteritis Nodosa (PAN ... (RA), Systemic lupus ... erythematosus ( ... SLE), Sarcoidosis
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
erythematosus ... • Fever is the main ... erythematosus [ ... SLE], AOSD) • Infection ... Histopathologic criteria
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Petechial Rash - Differential ... lesions • Severe pain ... Autoimmune Vasculitis (lupus ... Measurement of antinuclear ... Algorithm #Causes #dermatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential ... such as systemic lupus ... erythematosus, ... LFT • ESR • ANA ... SLE) • Urinalysis