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diagnosis rheumatology management activation ana antinuclear autoantibodies classification comparison druginduced eularacr hematology macrophage mas muscle myopathy sams statin syndrome toxicity
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
for Systemic Lupus ... Erythematosus ... Highly specific antibodies ... #SLE #Systemic ... #Lupus #Erythematosus
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... and Systemic lupus ... autoantibodies #Systemic ... #lupus #erythematosus ... #rheumatology #table
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
constitutional symptoms • Treatment ... months to years) Systemic ... Lupus Erythematosus ... life-threatening • Treatment ... #table #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
lupus erythematosus ... lupus erythematosus ... [SLE], AOSD) • ... Histopathologic criteria ... Treatment: • Corticosteroids
Statin Induced Muscle Toxicity - Summary Clinical Presentation: • Elevations of serum creatine kinase with proximal myalgia
syndrome (GBS), systemic ... lupus erythematosus ... (SLE), polymyositis ... syndrome (LEMS), systemic ... myopathy (IMNM) → Antibodies
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