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diagnosis rheumatology ana antibodies pathophysiology activation anca antineutrophil arthritis classification differential disease diseases hematology hypersensitivity hypersensitivityreaction imdamnsharp immunology laboratory macrophage
I’M DAMN SHARP - Lupus Diagnosis Mnemonic I Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid) M Malar Rash D
Discoid Rash A Antinuclear ... Antibody (ANA) ... #IMDAMNSHARP #sle ... #systemic #lupus ... #erythematosus
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
lupus erythematosus ... lupus erythematosus ... lupus erythematosus ... (SLE), Systemic ... (SLE), Systemic
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... - Summary Antinuclear ... /systemic sclerosis ... #Lupus #Erythematosus ... #rheumatology #management
Type III Hypersensitivity: Pathogenesis and clinical findings Definition: Small antigen-antibody complexes (produced from normal immune response to
Small antigen-antibody ... the cause: • Systemic ... Lupus • Erythematosus ... (SLE) If bacterial ... HypersensitivityReaction #Allergy
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
ANA (Antinuclear ... antibodies) • Systemic ... lupus erythematosus ... in drug-induced SLE ... ) • Systemic sclerosis
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
- Local and systemic ... - IgG or IgM antibody ... - Red blood cell ... arthritis, and systemic ... lupus erythematosus
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
lupus erythematosus ... lupus erythematosus ... [SLE], AOSD) • ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
affected joint • Systemic ... lupus erythematosus ... (SLE) - Antinuclear ... antibody (ANA) ... peptide (CCP) antibody
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