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diagnosis rheumatology syndrome classification complications erythematosus hematology hypersensitivity macrophage management manifestations mas mucocutaneous oncology reactions signs sweet symptoms table types
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
- Local and systemic ... - Red blood cell ... Complement activation ... lupus erythematosus ... Classification #Pathophysiology
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... Scaring alopecia • Red ... inflammation on skin ... Malar (butterfly) Rash ... Manifestations #pathophysiology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Female • Peaks 3rd ... Decade Skin ... Chronic B-cell activation ... #Systemic #Lupus
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... lupus erythematosus ... Petechial or purpuric rash ... lupus erythematosus ... [SLE], AOSD) •
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
sudden onset of a rash ... - Rash: multiple ... CANDLE syndrome - Allergic ... ’s syndrome - Lupus ... Syndrome #diagnosis #dermatology
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