13 results
Causes of Splenomegaly - Differential Diagnosis Algorithm
Infectious
 • Bacterial
 • Viral (EBV)
 • Parasitic
 • Fungal
Congestive
Causes of Splenomegaly ... Hepatic, Portal, Splenic ... Spherocytosis • Acquired causes ... Diagnosis #Algorithm #Causes ... #Hematology
Capnocytophaga Canimorsus Skin Rash

40 M presents w/ N, V, severe epigastric pain. SHx: smoker, drinks 18
dogs & latter can cause ... gram-negative bacillus cause ... underlying r.f as asplenia ... patients who are asplenic ... University Infectious Diseases
Acute Purpura Fulminans Skin Rash on Physical Exam 
60 year old male ITP s/p splenectomy 
1d
rigors, diarrhea, nausea ... Vibrio, aeromonas, Capnocytophaga ... in setting of asplenia ... BIDMC Infectious Diseases ... BIDMC_IDFellows #Capnocytophaga
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... in Sickle Cell Disease ... Common d/t impaired splenic ... Pain #SickleCell #Disease ... #hematology
Causes of Ascites - Differential Diagnosis Algorithm
Portal Hypertension - Prehepatic:
 • Portal vein thrombosis
 • Splenic
Causes of Ascites ... thrombosis • Splenic ... • Infiltrative disease ... Diagnosis #Algorithm #Hepatology ... #causes
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
Post-Hepatic: • Cardiac causes ... • Infiltrative diseases ... Veno-occlusive disease ... thrombosis • Splenic ... #hepatology
Capnocytophaga
GNR with long fusiform shape.  Fastidious facultative anaerobe that grows slowly and needs enriched agar
C.
Capnocytophaga GNR ... = most common cause ... of severe disease ... factors for severe disease ... immunocompromised host, asplenia
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
emboli: Cerebral > Splenic ... Septic Emboli Cause ... Treat underlying cause ... Endocarditis #diagnosis #management ... #cardiology
Causes of Fever in the Immunocompromised Host - Differential Diagnosis Algorithm
Structural Defect - Asplenia/HypospIenism
 • Bacteremia/Septic
Causes of Fever ... Structural Defect - Asplenia ... • Periodontal Disease ... Diagnosis #Algorithm #Causes ... #Hematology
Endocarditis - Overview and Differential Diagnosis Framework

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV
Congenital heart disease ... emboli: Cerebral > Splenic ... Septic emboli cause ... Treat underlying cause ... Differential #Diagnosis #cardiology