21 results
Cutaneous manifestations associated with myelodysplastic syndrome
 • Myeloid hemopathy with the most frequent skin lesions (20%)
frequent skin lesions ... • Significant lesion ... myelodysplastic #syndrome #differential ... #diagnosis #dermatology ... #oncology #clinical
Pathologic / Fragility Fractures - Differential Diagnosis Algorithm 
Tumours
 - See Bone Lesions Scheme
Paget's Disease
 -
- Differential ... Diagnosis Algorithm ... Tumours - See Bone ... Lesions Scheme ... #Orthopedics #Causes
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
predispose to other orthopedic ... • Differentiate ... SickleCell #Disease #differential ... #diagnosis #causes ... #hematology
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
g/dl LLN B - Bony ... lesions +1 or ... more: • Clonal bone ... Gammopathies #MGUS #diagnosis ... #hematology #oncology
Soft Tissue Lesions - Differential Diagnosis Algorithm 
Septic
 • Septic Bursitis
 • Necrotizing Fasciitis
 • Septic
- Differential ... Diagnosis Algorithm ... BoneFracture ... • Fracture Skin ... #Orthopedics #Causes
Anterior Shoulder Dislocation - ED Management
The shoulder is the most commonly dislocated major joint, 95% of
(10%), bony Bankart ... lesions (5%, fracture ... Radiology #XRay #Diagnosis ... #Management #Orthopedics ... #Sports #MSK
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... hemorrhagic skin lesions ... Drug induced - Bone ... #Diagnosis #hematology ... #nonpalpable #dermatology
Fluid-filled Rash - Diagnostic Algorithm.  Pustule: 1) Pustules more commonly suggest an infectious process (bacterial,
Fluid-filled Rash - Diagnostic ... Vesiculobullous lesions ... basement membrane zone ... #Diagnosis #Dermatology ... Bullous #Algorithm #Differential
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Pustular skin lesions ... anterior chest wall, parts ... • A clinical diagnosis ... #diagnosis #management ... #Dermatology
Indications for Serum Protein Electrophoresis (SPEP)
 • Suspected multiple myeloma, Waldenström's macroglobulinemia, primary amyloidosis, or related
loss, fatigue, bone ... Unexplained pathologic fracture ... or lyric lesion ... Electrophoresis #SPEP #Hematology ... #Diagnosis