67 results
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm
No Objective Weakness
 • Cardio-pulmonary disease
of Peripheral Weakness ... muscular atrophy • Hodgkin's ... Lambert-Eaton Myasthenic Syndrome ... Dystrophy • Statin ... #Neurology #Differential
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Neuromuscular Weakness ... Demyelinating Disease (MS ... heavy metals), Critical ... poisoning, Scorpion sting ... differential #diagnosis #neurology
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
Toxicity - Summary Clinical ... proximal myalgia and weakness ... symmetric muscle weakness ... Guillain-Barré syndrome ... IU/I • SAMS clinical
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
effects of SCC or Hodgkin ... Clinical Picture ... Imaging - CT Chest ... immunologic assay - MuSK ... diagnosis #management #neurology
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Pathogenesis and clinical ... Upper extremity weakness ... anesthesia. leg weakness ... signs #symptoms #msk ... #orthopedics #neurology
Neurological Manifestations of Tuberculosis
Spinal Arachnoiditis & Polyradiculopathy:
 • Subacute onset of limb weakness, bladder/bowel dysfunction, muscle
onset of limb weakness ... tubercles • Limb weakness ... Reconstitution Inflammatory Syndrome ... Worsening of previous neurologic ... differential #TB #neurology
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
• Acute stroke syndromes ... Paraneoplastic syndrome ... Lambert-Eaton - Isaacs' syndrome ... toxins: Steroids, Statins ... Differential #Diagnosis #neurology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... meningococcal, H1N1) Clinical ... Guillain-Barre Clinical ... Miller Fisher Syndrome ... management #treatment #neurology
Generalized Weakness - Differential Diagnosis Framework
"l feel weak":
 • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis
 •
Generalized Weakness ... Myopathy: Drugs (statin ... Rhabdomyolysis, Critical ... #Generalized #Weakness ... Diagnosis #causes #neurology
Lesions of the Spinal cord - Spinal Cord Syndromes

Spinal cord lesions can result in permanent neurologic
result in permanent neurologic ... findings: - Weakness ... result in: - Weakness ... in: - Muscle weakness ... differential #diagnosis #neurology