36 results
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm
No Objective Weakness
 • Cardio-pulmonary disease
- Differential Diagnosis ... muscular atrophy • Hodgkin's ... Lambert-Eaton Myasthenic Syndrome ... Dystrophy • Statin ... #Neurology #Differential
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Pathogenesis and clinical ... #diagnosis #pathophysiology ... #signs #symptoms ... #msk #orthopedics ... #neurology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
effects of SCC or Hodgkin ... - Peek sign ... Imaging - CT Chest ... aspiration and acute ... #management #neurology
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Neuromuscular Weakness ... Demyelinating Disease (MS ... heavy metals), Critical ... #differential #diagnosis ... #neurology
NINDS Diagnostic Criteria for Guillain Barre Syndrome 
Features Required for Guillain-Barré Syndrome:
 • Progressive muscle weakness
Progression of weakness ... sensory symptoms or signs ... nervous system signs ... hexacarbon abuse • Acute ... #neurology #neuropathy
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... Spasm, Cramping, Weakness ... stimulation Clinical ... symptoms) • Acute ... #management #neurology
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Diagnosis Framework ... Impairment: • Acute ... Lack of UMN/LMN signs ... toxins: Steroids, Statins ... #neurology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
- Summary Acute ... Guillain-Barre Clinical ... Guillain-Barre Diagnosis ... variants: (1) acute ... #treatment #neurology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... and Differential Diagnosis ... investigations depending on clinical ... context and signs ... #Acute #Kidney
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Cauda Equina Syndrome ... Complications: • Weakness ... pain (shooting, stabbing ... #MSK #pathophysiology ... #diagnosis #symptoms