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diagnosis nephrology management hyponatremia alkalosis behcet causes chloride criticalcare defects epithelial hypokalemia hypotonic inherited kidney metabolic pathophysiology physiologic rhabdomyolysis rheumatology
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Gitelman Syndrome ... Muscle weakness, dizziness ... ratio 0.5%) Differential ... • Autoimmune disease ... Rhabdomyolysis Treatment
Inherited Defects in Kidney Tubule Epithelial Cells Renal glucosuria - Na+-dependent glucose cotransporter Cystinuria - Amino acid transporter Bartter
ascending limb Gitelman ... cell epithelial sodium ... of epithelial sodium ... #Diagnosis #Differential ... #Table
Hyponatremia - Differential Diagnosis Algorithm Hypovolemic - Give volume Hypervolemic (Edematous) - Look for and treat underlying cause
Hyponatremia - Differential ... Diagnosis Algorithm ... cirrhosis, nephrotic syndrome ... #diagnosis #nephrology ... #sodium
Shock - Differential Diagnosis Framework - MAP <65. SBP <90, drop in SBP > 40 -
Shock - Differential ... , Severe Valve Disease ... Abdominal compartment syndrome ... #criticalcare #algorithm ... #treatment #management
Metabolic Alkalosis - Urinary Chloride Algorithm Cl- responsive metabolic alkalosis • Kidney loss of Cl-
Urinary Chloride Algorithm ... diuretic use, Bartter syndrome ... , Gitelman syndrome ... the excretion of sodium ... #nephrology #differential
Physiologic Approach to Hypotonic Hyponatremia The next time you have a case of hypotonic hyponatremia, give the
normal volume-based algorithm ... Cirrhosis, Nephrotic syndrome ... #Hyponatremia #differential ... #diagnosis #table ... #sodium #nephrology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
skin injury) • Neurologic ... Medium and large ... (SVC/IVC occlusion ... ) Differential Diagnosis ... Arthritis, AS Treatment
Hyponatremia - Diagnosis and Treatment Hyponatremia is usually caused by the inability to excrete water normally.
approach to the differential ... demyelination syndrome ... vaptans (HF/liver disease ... #management #nephrology ... #sodium
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Rhabdomyolysis - Differential ... disease 2. ... per day until stable ... Rhabdomyolysis #Differential ... #nephrology
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