13 results
IBS-C Pharmacotherapy

Polyethylene glycol
Lubiprostone
Linaclotide
Plecanatide
Tegaserod
Tenapanor

#IBSC #IBS #Constipation #Irritable #Bowel #Syndrome #pharmacology #table #comparison #management #treatment
IBS-C Pharmacotherapy ... Irritable #Bowel #Syndrome ... #pharmacology # ... table #comparison ... #management #treatment
IBS-D Pharmacotherapy

Loperamide
Rifaximin
Eluxadoline
Alosetron
Antispasmodics
Tricyclic antidepressants
SSRIs

#IBSD #IBS #Diarrhea #Irritable #Bowel #Syndrome #pharmacology #table #comparison #management #treatment
IBS-D Pharmacotherapy ... Irritable #Bowel #Syndrome ... #pharmacology # ... table #comparison ... #management #treatment
Shock - Differential Diagnosis Framework
 - MAP <65. SBP <90, drop in SBP > 40
 -
Shock - Differential ... Abdominal compartment syndrome ... Treatment Goals ... #Differential # ... #management
Comparison of anti-diabetic or anti-hyperglycemic agents

There are numerous anti-hyperglycemic agents available to manage Type 2 diabetes.
Comparison of anti-diabetic ... #pharmacology #pharmacotherapy ... #table #comparison ... #management #medications ... endocrinology #treatment
Pressors and Inotropes

Norepinephrine
 • alpha1 > beta 1
 • Increase SVR > Inotropy
Vasopressin
 • V1
 •
1 • Increase SVR ... 1 • Increase SVR ... #criticalcare #pharmacology ... #comparison #shock ... #management
Shock - Differential Diagnosis Framework
MAP = CO x SVR
Hypovolemic (↓ Intravascular volume):
 • Hemorrhage, dehydration due
Shock - Differential ... anaphylaxis, release syndrome ... uw_IMresidency #Shock ... #Differential # ... Diagnosis #table #comparison
Approach to Undifferentiated Shock - OnePager Summary
Shock occurs when there is inadequate blood flow (CO) &
essential to determine treatment ... CCB, BB, BRASH syndrome ... Pipes Problem (↓ SVR ... cytokine release syndrome ... #diagnosis #differential
Fever vs Hyperthermia
Fever:
 • Regulated in the hypothalamic thermoregulatory center
 • "Set point" raised by prostaglandin
Neuroleptic malignant syndrome ... ; Serotonin syndrome ... #Hyperthermia #comparison ... #diagnosis #management ... #treatment
Systemic Inflammatory Response Syndrome (SIRS)
•	Non-specific (infections vs non-infectious)
•	≥2 of the following:
o	Temp >38°C or <36°C
o	HR >90 bpm
o	RR
Inflammatory Response Syndrome ... Septic Shock • ... >2 mmol/L Management ... recognition & treatment ... glycemic control, DVT
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Infection/Sepsis/Shock ... Reversible course Differential ... epilepticus Treatment ... underlying cause • Treatment ... #diagnosis #management