11 results
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
Approach to Thrombotic ... Diagnosis and Management ... Reticulocytes, smear ... MAHA likely: • Smear ... #Algorithm #hematology
Differential diagnosis of schistocytes / fragmentation hemolysis:
 • Thrombotic microangiopathies (TMA)
    - TTP
Differential diagnosis ... hemolysis: • Thrombotic ... hemolytic-uremic syndrome (ST-HUS ... macroangiopathic hemolytic anemia ... #diagnosis #hematology
Causes of Breakthrough/Extension of Thrombosis and Management Algorithm

#Anticoagulation #Breakthrough #Thrombosis #Algorithm #Extension #VTE #DVT #Hematology #Management
and Management ... #Breakthrough #Thrombosis ... Extension #VTE #DVT ... #Hematology #Management ... #Diagnosis #Differential
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
Diagnosis and Management ... 5-10d, venous (DVT ... Diagnosis: • Clinical ... non-heparin A/C if clinical ... #Treatment #Hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
Evaluation for Thrombotic ... result in severe anemia ... Peripheral blood smear ... WBC count and differential ... Diagnosis #Workup #Hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
• Peripheral smear ... immunophenotype Clinical ... 5) Symptoms of anemia ... Leukemia #oncology #hematology ... hemeonc #diagnosis #management
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
organ damage Clinical ... • Peripheral smear ... - bleeding or thrombosis ... causes #treatment #management ... #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Viral Infection Clinical ... • Symptoms of anemia ... IgM) • Blood smear ... younger pts) Differential ... #hematology #diagnosis
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
(-) hemolytic anemia ... Hyperviscosity (Thrombosis ... beds-renal, retinal, DVT ... Paraproteinemias #Hematology ... #Monoclonal #Differential
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... Venous disease (SVC ... syndrome, dural sinus thrombosis ... Behcet disease) Differential ... Syndrome #diagnosis #management