31 results
Differential diagnosis of schistocytes / fragmentation hemolysis:
 • Thrombotic microangiopathies (TMA)
    - TTP
Differential diagnosis ... hemolysis: • Thrombotic ... hemolytic-uremic syndrome ... (ST-HUS) - ... #diagnosis #hematology
Approach to Headaches - Differential Diagnosis Algorithm

Red flags (PHANTOMS):
 • Pattern change, progressively worse, papilledema
 •
Diagnosis Algorithm ... papilledema • Horner syndrome ... ) • Systemic symptoms ... and signs (e.g., fever ... Cerebral venous thrombosis
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Dehydration • Symptoms ... changes, stroke symptoms ... - 80% have fever ... #TLS #diagnosis ... #management #hematology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
, dural sinus thrombosis ... Behcet disease) Differential ... Arthritis, AS Treatment ... #signs #symptoms ... #rheumatology #
Neurological Manifestations of Tuberculosis
Spinal Arachnoiditis & Polyradiculopathy:
 • Subacute onset of limb weakness, bladder/bowel dysfunction, muscle
Reconstitution Inflammatory Syndrome ... , fever, inccreased ... infarction, vasospasm, thrombosis ... #Tuberculosis #diagnosis ... #differential #
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Subacute-Acute: • Common: fever ... : >3 symptoms, or ... initiation • Differential
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... permanent alopecia Differential ... Induced Lupus: • Symptoms ... to: Arthritis, Fever ... #Rheumatology
Palpitations - Differential Diagnosis Framework

What?
• It is an unpleasant awareness or sensation that the heart is
Palpitations - Differential ... Diagnosis Framework ... Electrolyte imbalance • Fever ... AVNRT Red Flag Symptoms ... Palpitations #Cardiology #Differential
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Organomegaly+↑RBC/plt+, ↑thrombosis ... Hyperviscosity (Thrombosis ... beds-renal, retinal, DVT ... #Monoclonal #Differential ... #Diagnosis #Oncology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Rhabdomyolysis - Differential ... Diagnosis Framework ... : • Triad of symptoms ... urine • Other symptoms ... Muscle swelling - Fever