7548 results
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
evaluation of the clinical ... blood tests, synthetic ... /or suspicious clinical ... the remainder, a clinical ... elevation and clinical
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
>10 mmHg - clinically ... Preserved hepatic synthetic ... sarcoidosis) • Liver ... metastasis • Fatty liver
5-Oxoprolinuria
What is it:
 • Aka pyroglutamic acidosis, Intermediate in γ-glutamyl cycle
 • Amino acid transport and
and glutathione synthesis ... paracetamol ingestion Clinical ... deficiency) • Liver ... high index of clinical
Functions of the Liver

Storage 
Degradation 
Metabolism 
Synthesis 

#Pathophysiology #Functions #Liver #Hepatology #Synthesis #Storage #Metabolism
Functions of the Liver ... Metabolism Synthesis ... Pathophysiology #Functions #Liver ... #Hepatology #Synthesis
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
organ damage Clinical ... DIC • Severe Liver ... : - Impaired synthesis
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
Liver Chemistry ... In liver, 80% of ... phosphatase: • Synthesis ... due to increased synthesis ... clearance - AP synthesis
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... Causes of Acute Liver ... salts augment synthesis ... ALP - Due to synthesis ... source - Tests of synthetic
Antibiotic Classification by Mechanism of Action

Cell Wall Synthesis: 
Penicillins 
Cephalosporins 
Carbapenems 
Monobactams 
Beta-lactamase inhibitors
Glycopeptides 

 Protein
Action Cell Wall Synthesis ... Glycopeptides Protein Synthesis ... Folic Acid Synthesis ... Metronidazole mRNA Synthesis ... Recommended Text: Clinical
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Liver Chemistries ... Identify Acute Liver ... - Specific to liver ... salts augment synthesis ... ALP - Due to synthesis
Pharmaceutical Management of Hyperthyroidism / Thyroid Storm
Beta-Blockers 
• Decreases sympathetic hyperactivity 
• Partially blocks peripheral conversion
PTU) • Blocks synthesis ... Methimazole • Blocks synthesis ... Administer only after synthetic