10 results
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
with cytotoxic T ... IV - T cells - ... cytokines, which activate ... #Classification ... #Pathophysiology
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
tissues where they activate ... activate Th1/cytotoxic ... T cells. ... T-cells recruit ... allergy #table #classification
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
it is entirely T-Cell ... allergen-specific T-Cell ... exposure, because T-Cell ... activate macrophages ... Allergy #Immunology #pathophysiology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... as common - T ... Lymphoproliferative #Disorders #Classification ... #pathophysiology ... #differential #algorithm
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
allergens and activate ... it is entirely T-Cell ... allergen-specific T-Cell ... exposure, because T-Cell ... #Classification
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
increases out of cells ... Vaughan Williams Classification ... node and AV node activity ... ++ influx into cells ... #Classes #pathophysiology
Recommended initial testing for patients being evaluated for glomerular disease 

24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... decreased red cell ... disorders that activate ... cryoglobulinemias (types ... #workup #diagnosis
Recommended initial testing for patients being evaluated for glomerular disease
1) 24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... decreased red cell ... disorders that activate ... cryoglobulinemias (types ... glomerular #disease #workup
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... Kikuchi disease • Type-I ... Angioimmunoblastic T-cell ... extremity edema, active ... : • Chronic B-cell
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
Types of HLH • ... Pathophysiology ... and CD8+ T cells ... Low/absent NK-cell ... activity g