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diagnosis differential allergy cardiology classification clinical echocardiogram hypersensitivity types cardiac dermatology effusion pericardial table tamponade a4c allergic anticonvulsants bands basophils
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
hypersensitivity reactions ... Allergen-specific lgE causes ... Antigen-antibody complex ... Antigen-antibody complexes ... T-cells recruit
Type IV Hypersensitivity: Pathogenesis and clinical findings Definition: Unique because it is entirely T-Cell mediated; exposure to
it is entirely T-Cell ... exposure to allergen causes ... allergen-specific T-Cell ... Allergic reaction ... exposure, because T-Cell
Hypersensitivity: Definitions • Type I - Production of lgE Abs that bind to harmless allergens and
surfaces causes ... antigen-surface complex ... it is entirely T-Cell ... allergen-specific T-Cell ... exposure, because T-Cell
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
with cytotoxic T ... Antigen-antibody complexes ... and cytotoxic T ... Classification #Pathophysiology ... Allergy #Diagnosis #Reactions
Erythroderma - Diagnostic Algorithm. Pathophysiology: 1) Extensive cutaneous capillary dilation, results in widespread exfoliation of the
Erythroderma - Diagnostic Algorithm ... Pathophysiology: ... germinative skin cells ... Causes: 1) Exfoliative ... 4) Skin-homing T-cells
Evaluation of Leukocytosis: The term 'leukocyte' applies to any cells within the myeloblast, monoblast, & lymphoid lineages. Include
Evaluation of Leukocytosis ... , T cells, and natural ... Leukemoid reaction ... Morphologically: absence of complete ... the underlying cause
Skin Ulcers by Etiology - Differential Diagnosis Algorithm Physical: • Trauma • Pressure • Radiation Vascular: • Arterial
Differential Diagnosis Algorithm ... fungoides (cutaneous T-cell ... Viral - Herpes simplex ... Differential #Diagnosis #Algorithm ... #causes
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Disorders Testing Algorithm ... during medical evaluation ... Eosinophilia, 500-1,500 cells ... for secondary causes ... allergy, drug reaction
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect Examples: Valproate, Carbamazepine, Lamotrigine • Mild anticholinergic effect -> Drowsiness
constipation • Allergic reaction ... Benign Rash • T-cell ... mediated cytotoxic reaction ... Systemic effect -> Nausea ... #SideEffects #Pathophysiology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Activation of CD8 T ... Hemopathies+++: Hodgkin, T-cell ... Drugs, Unknown cause ... inhibitors under evaluation
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