16 results
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Allergen-specific lgE causes ... Anaphylaxis, Hay fever ... Antigen-antibody complex ... T-cells recruit ... allergy #table #classification
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
, seasonal hay fever ... with cytotoxic T ... Antigen-antibody complexes ... and cytotoxic T ... Hypersensitivity #Types #Classification
Serious Bacterial Illness (SBI):
1) UTI and pyelonephritis
Most common cause of SBI
Accounts for 3-8% of uncharacterized fevers
Female
pyelonephritis Most common cause ... uncharacterized fevers ... Consider BCx, CSF evaluation ... (particularly complex ... Diagnosis #Peds #EM #Classification
Skin Ulcers by Etiology - Differential Diagnosis Algorithm
Physical:
 • Trauma
 • Pressure
 • Radiation
Vascular:
 • Arterial
Differential Diagnosis Algorithm ... fungoides (cutaneous T-cell ... Viral - Herpes simplex ... Differential #Diagnosis #Algorithm ... #causes
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Activation of CD8 T ... • Clinical: fever ... Hemopathies+++: Hodgkin, T-cell ... Drugs, Unknown cause ... inhibitors under evaluation
Evaluation of Leukocytosis:
The term 'leukocyte' applies to any cells within the myeloblast, monoblast, & lymphoid lineages.
Include
Evaluation of Leukocytosis ... , T cells, and natural ... neutropenia: typhoid fever ... Morphologically: absence of complete ... the underlying cause
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
surfaces causes ... it is entirely T-Cell ... allergen-specific T-Cell ... exposure, because T-Cell ... Reactions #Types #Classification
Causes of Fever in the Immunocompromised Host - Differential Diagnosis Algorithm
Structural Defect - Asplenia/HypospIenism
 • Bacteremia/Septic
Causes of Fever ... Encapsulated Bacteria Cell ... Mediated Immunity - T-Cells ... Infection #Fever ... #Causes #Hematology
Modified dengue severity classification, PAHO/WHO
Dengue without warning signs - DNWS:
 • Person who lives or has
dengue severity classification ... days and presents fever ... and no apparent focus ... bleeding: based on evaluation ... organs #dengue #fever
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
presentation, temporal evolution ... therapy Herpes Simplex ... • Symptoms: Fever ... • Symptoms: Fever ... Demyelinating disease caused