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diagnosis management differential hematology immunology treatment classification nephrology tuberculosis allergy disorders endocrinology glomerular hemeonc inflammatory latenttb nephrotic neurology pharmacology table
Type IV Hypersensitivity: Pathogenesis and clinical findings Definition: Unique because it is entirely T-Cell mediated; exposure to
it is entirely T-Cell ... allergen-specific T-Cell ... exposure, because T-Cell ... activate macrophages ... Allergy #Immunology #pathophysiology
Inflammatory mechanism of asthma. Airway epithelial cells exposed to activation stimuli, including allergens, viruses, and irritants,
Airway epithelial cells ... antigens and thereby activate ... naive CD4 T cells ... These T cells then ... #asthma #pathophysiology
Inflammatory Cascade: Pathogenesis and Clinical Findings Continued Innate Immunity • Phagocytosis: (main mechanism) neutrophils and macrophages engulf
Natural Killer Cells ... • Humoral: (B cell ... : (T cell response ... activity #Inflammatory ... #Inflammation #pathophysiology
Humoral Immunity - Pathogenesis and Clinical Findings Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
cells and activate ... B cells • T cell-independent ... neutralizing them - Activate ... Complement: Abs activate ... Humoral #Immunity #pathophysiology
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
with cytotoxic T ... erythematosus Type IV - T ... cytokines, which activate ... and cytotoxic T ... Classification #Pathophysiology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Algorithm INDICATIONS ... evaluation or workup ... Eosinophilia, 500-1,500 cells ... Hypereosinophilia, >1,500 cells ... /µL Workup • Screen
Hypoglycemia - Evaluation Algorithm Interpreting Hypoglycemia Labs - the patient must be hypoglycemic at the time of
Hypoglycemia - Evaluation Algorithm ... at the time of testing ... Malignancy (islet cell ... Hypoglycemia #Evaluation #Algorithm ... #workup #diagnosis
Erythroderma - Diagnostic Algorithm. Pathophysiology: 1) Extensive cutaneous capillary dilation, results in widespread exfoliation of the
Erythroderma - Diagnostic Algorithm ... Pathophysiology: ... germinative skin cells ... 4) Skin-homing T-cells ... Erythroderma #Nikolsky #Algorithm
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... as common - T ... Cell ~10% - B-Cell ... Classification #pathophysiology ... #differential #algorithm
Intraoperative Massive Blood Loss - Guidelines for Crises in Anaesthesia Expected or unexpected major haemorrhage ❶ Call for
with them): • Activate ... required. ❻ Begin active ... point of care testing ... • Use lab testing ... Diagnosis #Management #Workup
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