7 results
Shock Overview
A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
death -> end-organ dysfunction ... #Classification ... #diagnosis #management ... #criticalcare #differential ... #causes #classification
Shock Types - Classification
State of cellular and tissue hypoxia due to: reduced oxygen delivery, increased oxygen
Shock Types - Classification ... END-ORGAN DYSFUNCTION ... #Classification ... types #diagnosis #management ... #criticalcare #differential
Shock Overview
A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
death -> end-organ dysfunction ... #Classification ... #diagnosis #management ... #criticalcare #differential ... #causes #classification
SEPSIS AND SEPTIC SHOCK

DEFINITION AND PATHOPHYSIOLOGY
 • Sepsis: Life-threatening organ dysfunction due to a dysregulated host
DEFINITION AND PATHOPHYSIOLOGY ... • Pathophysiology ... • Symptoms: Fever ... INITIAL MANAGEMENT ... ADVANCED MANAGEMENT
Causes of Fever in the Immunocompromised Host - Differential Diagnosis Algorithm
Structural Defect - Asplenia/HypospIenism
 • Bacteremia/Septic
Causes of Fever ... Diagnosis Algorithm ... Bacteremia/Septic Shock ... or Neutrophil Dysfunction ... Infection #Fever
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... Subacute-Acute: • Common: fever ... initiation • Differential ... severe APLS, organ dysfuxtion ... APML #diagnosis #management
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Infection/Sepsis/Shock ... Etiology: • Pathophysiology ... unclear, endothelial dysfunction ... Reversible course Differential ... Syndrome #diagnosis #management