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diagnosis management hematology hemophagocytic lymphohistiocytosis causes differential hemeonc immunecompromised immunocompromised rheumatology sepsis septic septicshock summary treatment
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH ... ) Pathophysiology ... • Clinical: fever ... , Hb), Hepatic dysfunction ... • Familial HLH
SEPSIS AND SEPTIC SHOCK DEFINITION AND PATHOPHYSIOLOGY • Sepsis: Life-threatening organ dysfunction due to a dysregulated host
DEFINITION AND PATHOPHYSIOLOGY ... Life-threatening organ dysfunction ... cellular/metabolic dysfunction ... • Pathophysiology ... • Symptoms: Fever
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
cytopenias and organ dysfunction ... , organ dysfunction ... Persistent high fever ... Pathophysiology ... Fever b.
Causes of Fever in the Immunocompromised Host - Differential Diagnosis Algorithm Structural Defect - Asplenia/HypospIenism • Bacteremia/Septic
Causes of Fever ... Differential Diagnosis Algorithm ... Bacteremia/Septic Shock ... or Neutrophil Dysfunction ... Infection #Fever
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