23 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome in APML ... ATRA treatment Pathophysiology ... initiation • Differential ... severe APLS, organ dysfuxtion ... Differentiation #Syndrome #APML
Lactic Acidosis - Overview and Pathophysiology
Lactic acid is an endogenous substrate for gluconeogenesis, that is constantly
- Overview and Pathophysiology ... Acidosis #types #differential ... #diagnosis #pathophysiology ... #classification
Hypomagnesemia - Etiologies by Mechanism

Decreased GI Uptake 
 - Poor dietary intake (particularly common in alcoholics)
renal tubular dysfunction ... Hypomagnesemia #Differential ... Magnesium #Table #Classification
Causes, classification and compensatory responses to shock.

Shock can be caused by any pathological process that leads
Causes, classification ... vasodilatation, myocardial dysfunction ... CriticalCare #Shock #Differential ... Causes #Types #Classification
Clinical Classification of Pulmonary Hypertension

1. Pulmonary arterial hypertension from pulmonary vasculopathy
Idiopathic pulmonary arterial hypertension
Heritable gene mutations
Clinical Classification ... disease Systolic dysfunction ... Diastolic dysfunction ... Hypertension #PHTN #Classification ... #Diagnosis #Differential
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... hepatocytes → Liver dysfunction ... infiltration) Differential ... diagnosis #management #pathophysiology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders - Differential ... Lymphoproliferative #Disorders #Classification ... #pathophysiology ... Diagnosis #NonHodgkin #differential
Schematic representation of the major sources of ammonia production and its excretory pathway (GI = gastrointestinal,
myeloma, CML, AML ... deficiency #Ammonia #Pathophysiology ... Hyperammonemia #Differential
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework

Heat Cramps:
 • Muscle pain or spasm -
Heat Stroke - Differential ... Collapse: • Pathophysiology ... significant CNS dysfunction ... CNS dysfunction ... heat #illness #differential
Shock Overview
A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
death -> end-organ dysfunction ... EmmGeezee #Shock #Classification ... #criticalcare #differential ... #causes #classification