49 results
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
Systemic Sclerosis ... Scleroderma) Multi-system ... calcinosis • Pulmonary ... disease), PAH (pulmonary ... Scleroderma #SSc #rheumatology
RASHonal Approach to a Rash

- Dr. Arielle Klepper @ https://twitter.com/ArielleKlepper

#Rash #Algorithm #RASHonal #Differential #Diagnosis #Classification #Skin
Algorithm #RASHonal #Differential ... #Diagnosis #Classification ... #Skin #Dermatology
Systemic Sclerosis Associated Autoantibodies
Anti-topoisomerase I (anti-Sc170): Diffuse skin disease, Pulmonary fibrosis
Anti-centromere: Limited skin disease (~93-95%), Pulmonary
Systemic Sclerosis ... disease, Pulmonary ... disease (~93-95%), Pulmonary ... BCM_InternalMed #Systemic ... Autoantibodies #diagnosis #rheumatology
Clinical Classification of Pulmonary Hypertension

1. Pulmonary arterial hypertension from pulmonary vasculopathy
Idiopathic pulmonary arterial hypertension
Heritable gene mutations
Clinical Classification ... heart disease Systolic ... multifactorial mechanisms Hematologic ... disorders, lenectomy Systemic ... #Diagnosis #Differential
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
- Generalized Differential ... Causes == Primary Skin ... • Xerosis (dry skin ... Lesion / Systemic ... #generalized #dermatology
Hepatopulmonary Syndrome (HPS) 

HPS-differential diagnosis:
1. Pulmonary vasculature
2. Diseases of the lung parenchyma
3. Pleura and diaphragm

HPS-diagnosis:
1. Patients
(HPS) HPS-differential ... Pulmonary vasculature ... HPS-severity classification ... Syndrome #HPS #hepatology ... #pulmonary #diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Vasculitides - Differential ... progressing GN • New pulmonary ... well as inner ear ... #diagnosis #rheumatology ... #classification
Connective tissue disease-associated interstitial lung diseases

LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
SSc: systemic sclerosis ... arthritis SLE : systemic ... CTILD #Diagnosis #Differential ... Comparison #Table #Pulmonary ... #Rheumatology #
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Arthralgia/arthritis, Skin ... fraction < 20% Differential ... solid cancers • Systemic ... hepatitis • Pulmonary ... management #treatment #rheumatology
Causes of Pulmonary Hypertension - Differential Diagnosis Algorithm
Pulmonary Arterial Hypertension
 • Idiopathic
 • Associated with:
Causes of Pulmonary ... Hypertension - Differential ... Diagnosis Algorithm Pulmonary ... Dysfunction: • Systolic ... Miscellaneous: • Hematologic