54 results
Natural History of Syphilis
Primary - 2-6 weeks after infection
 • Chancre, Regional lymphadenopathy
Early Latent ≤ 1
Natural History of Syphilis ... Early Latent ≤ 1 year ... Late Latent - > 1 year ... (10%); Ocular syphilis ... #progression #diagnosis
Syphilis - Clinical Manifestations and Treatment

1) Primary Syphilis
 • Direct lesion contact during sex is responsible
Symmetric macular ... Albuminuria, nephrotic syndrome ... Headache, meningitis, ocular ... #stages #diagnosis ... #management #Treatment
Stages of Syphilis
Early Primary:
 • Painless chancre
 • Regional lymphadenopathy
Early Secondary:
 • Fever, malaise
 • Rash
Stages of Syphilis ... • Within first year ... • Gummatous • Nodular ... BostonChiefs #Syphilis ... symptoms #signs #diagnosis
The Stages of Syphilis 

Primary Syphilis 
- The chancre lesion is the hallmark of primary syphilis.
- Ocular syphilis ... and nephrotic syndrome ... within the last year ... roots, causing a syndrome ... Latent #Tertiary #Diagnosis
Isocoria - Pupillary Defects - Differential Diagnosis Algorithm
Relative Afferent Pupil Defect
 • Optic Neuritis
 • Ischemic
- Differential Diagnosis ... Pupils (Miotic) • Syphilis ... (light-near dissociation ... Midbrain (Parinaud's Syndrome ... #Differential #Diagnosis
Central Distribution, Febrile / Ill:
 - Viral Exanthem 
 - Lyme Disease (erythema migrans) 
Central Distribution,
Stevens-Johnson Syndrome ... meningococcaemia - Syphilis ... Maculopapular #Macular ... Rash #Algorithm #Diagnosis
Sensorineural Hearing Loss - Differential Diagnosis Algorithm

Asymmetric Sensorineural Hearing Loss: 
 • Neoplastic (Vestibular Schwannoma)
 •
- Differential Diagnosis ... Toxoplasmosis, HIV, Syphilis ... Cochlear (Inner-Ear ... Autoimmune (Cogan's Syndrome ... #Differential #Diagnosis
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
BEE Syndromes - ... Brain, Eye, and Ear ... important, as early diagnosis ... Infectious • Syphilis ... #differential #diagnosis
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
ulceration • Ocular ... artery aneurysms Diagnosis ... ) Differential Diagnosis ... Giant retinal tears ... #diagnosis #management
Uveitis - Definition, Causes and SUN Classification

Inflammation of the iris, ciliary body, vitreous, retina and/or choroid
Incidence
: 17-52 cases/year ... blindness, linked to macular ... tuberculosis, syphilis ... #Differential #Diagnosis