14 results
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
s Syndrome: Pathogenesis ... biliary cirrhosis ... (SLE) Signs / Symptoms ... - Decreased tear ... Diagnosis #Signs #Symptoms
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Primary Biliary ... Cirrhosis - Diagnosis ... Algorithm Symptoms ... #Biliary #Cirrhosis ... #hepatology
Hepatomegaly - Differential Diagnosis Algorithm
Malignant
 • Primary Carcinoma
 • Metastases
 • Lymphoma
 • Leukemia
 • Polycythemia
Differential Diagnosis Algorithm ... • Budd-Chiari Syndrome ... Biliary Cirrhosis ... Differential #Diagnosis #Algorithm ... #Causes #Hepatology
Causes of Ascites - Differential Diagnosis Algorithm
Portal Hypertension - Prehepatic:
 • Portal vein thrombosis
 • Splenic
Differential Diagnosis Algorithm ... - Hepatic: • Cirrhosis ... liver failure • Primary ... cholangitis • Primary ... #Hepatology #causes
Hyponatremia - Differential Diagnosis Algorithm
Hypovolemic - Give volume
Hypervolemic (Edematous) - Look for and treat underlying cause
Differential Diagnosis Algorithm ... underlying cause (CHF, cirrhosis ... , nephrotic syndrome ... Solute Intake - Primary ... Potomania - Tea
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs ... Elevation of ALP • Near ... hepatitis: < 1 • Cirrhosis ... • Gilbert's syndrome ... transaminitis #LFTs
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
function tests algorithm ... suspicious clinical symptoms ... presence of metabolic syndrome ... #LFTs #Abnormal ... #Algorithm #Hepatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... SLE), Sjogren's Syndrome ... Arthritis, Sjögren Syndrome ... Autoimmune Hepatitis, Primary ... Biliary Cirrhosis
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Vaginal dryness • Primary ... ab (specific in primary ... biliary cirrhosis ... Nephrogenic DI Hematologic ... Symptomatic: artificial tears
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
of 37°C to the near-freezing ... Cryofibrinogenemia Symptoms ... Primary (essential ... Antiphospholipid syndrome ... #hematology