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diagnosis management leukemia chronic cll comparison disease lymphocytic signs algorithm anemia aplastic apml behcet cancer capillary causes clarksons classification cryofibrinogenemia
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Dehydration • Symptoms ... changes, stroke symptoms ... , dyspnea, +/- CXR ... organ damage • Treatment ... diagnosis #management #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Diagnosis: >3 symptoms ... diagnosis #management #hematology ... #oncology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
Risk factors: Critical ... ARDS to explain symptoms ... fluid balance, and CXR ... Transfusion #Reactions #hematology ... diagnosis #comparison #table
Susac Syndrome - Clinical Triad - Central nervous system dysfunction - Branch retinal artery occlusion -
Susac Syndrome - ... Clinical Triad ... disease flares - 2-year ... arterioles - Treatment ... Diagnosis #Management #Rheumatology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
immunophenotype Clinical ... Splenomegaly 5) Symptoms ... Constitutional symptoms ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia Clinical ... aplastic anemia Treatment ... • Improve the symptoms ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... (Clinical Dx). ... Giant retinal tears ... Arthritis, AS Treatment ... #rheumatology #
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
renal failure Clinical ... e.g. incidental CXR ... Self-limiting, chronic but stable ... : (distinct symptoms ... ) • Löfgren syndrome
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... with no early symptoms ... microglobulin Treatment ... diagnosis #workup #oncology ... #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
develop leukostasis syndrome ... manifestations, hypoxia, CXR ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
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