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diagnosis hematology management chronic cll lymphocytic signs algorithm anemia aplastic apml behcet cancer causes classification comparison differential differentiation disease hemeonc
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... develop leukostasis syndrome ... manifestations, hypoxia, CXR ... • Tumor lysis syndrome ... #Hematology #Oncology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic Leukemia ... • Most common leukemia ... immunophenotype Clinical ... Constitutional symptoms ... #oncology #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... with no early symptoms ... microglobulin Treatment ... diagnosis #workup #oncology ... #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... common • Imaging: CXR ... Diagnosis: >3 symptoms ... #oncology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
(Clinical Dx). ... Giant retinal tears ... , Ischemia, Leukemia ... Arthritis, AS Treatment ... #rheumatology #
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia Clinical ... virus (EBV) • Leukemia ... aplastic anemia Treatment ... • Improve the symptoms ... Aplastic #Anemia #oncology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
Risk factors: Critical ... ARDS to explain symptoms ... : 33% • Treatment ... fluid balance, and CXR ... diagnosis #comparison #table
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
renal failure Clinical ... e.g. incidental CXR ... Self-limiting, chronic but stable ... : (distinct symptoms ... ) • Löfgren syndrome
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... Chronic Myelogenous Leukemia ... • Hairy Cell Leukemia ... #diagnosis #hematology ... #oncology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Dermatomyositis Clinical ... : • Triad of symptoms ... urine • Other symptoms ... ) • AKI: BUN/Cr ... per day until stable
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