10 results
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... initial response to abnormal ... presence of metabolic syndrome ... #Algorithm #Hepatology ... Liver #Enzymes #Differential
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... (Clinical Dx). ... Behcet disease) Differential ... Giant retinal tears ... Arthritis, AS Treatment
The Neurological Evaluation of a Comatose Patient

Definition:
 • Coma: a state of unresponsiveness; the absence of
consciousness Differential ... Unresponsive wakefulness syndrome ... • Locked-in syndrome ... • Mutism Pathophysiology ... If ok with ICU team
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Pathophysiology ... initiation • Differential ... 500 mg QD until normal
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
cases/100,000 per year ... Guillain-Barre Pathophysiology ... meningococcal, H1N1) Clinical ... Guillain-Barre Clinical ... CSF PROTEIN - NORMAL
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... per 100,000 per year ... and sensitive tests ... the underlying pathophysiology ... and cauda equina TREATMENT
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... Transverse Myelitis - Clinical ... Sjogren's • CSF: - Abnormal ... negative, MOG-IgG test ... Transverse Myelitis Treatment
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
GrepMed Handbook Clinical ... Differential Diagnosis ... Beckwith Wiedemann syndrome ... glucose suppression test ... Endocrinology #Treatment
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
tubule (DCT) Clinical ... Metabolic alkalosis • Normal ... ratio 0.5%) Differential ... Rhabdomyolysis Treatment ... nephrology #management #pathophysiology
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
Hepatorenal Syndrome ... Pathophysiology: ... Diagnosis (Clinical ... Treatment Overview ... #Hepatology #Nephrology