57 results
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
Multi-system autoimmune disease ... thickening Signs ... interstitial lung disease ... #diagnosis #signs ... symptoms #testing #workup
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
trigger - Direct skin ... 50% of patients Skin ... - Ice cube test ... , TempTest test ... Urticaria #diagnosis #rheumatology
Leser–Trélat Sign on Physical Exam

Acute onset of multiple seborrheic keratoses, often a paraneoplastic sign of malignancy.

#Leser
Leser–Trélat Sign ... paraneoplastic sign ... #LeserTrelat #Sign ... PhysicalExam #clinical #video ... #skin #dermatology
Breast Cancer - Visible Signs on Physical Examination:

Retraction, Abnormal Contours, Skin Dimpling, Nipple Retraction, Edema, Paget's
Cancer - Visible Signs ... Abnormal Contours, Skin ... Edema, Paget's Disease ... BreastCancer #Visible #Signs ... GrepMed Recommended Text
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... PT, aPTT(liver disease ... K), H. pylori test ... thyroid function test ... #hematology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
evaluation or workup ... 1,500 cells/µL Workup ... organ-specific signs ... symptoms (eg, skin ... Differential #diagnosis #hematology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
response to local skin ... (this is a skin ... prick test that ... diagnosis #management #signs ... #symptoms #rheumatology
Fever of Unknown Origin (FUO) - Further Workup

 • CNS symptoms? Get an LP and imaging
FUO) - Further Workup ... Test for the respective ... thin smear • Signs ... values supporting hematologic ... UnknownOrigin #workup
Nikolsky's Sign in Toxic Epidermal Necrolysis (TEN)

Nikolsky's sign is a clinical dermatological sign which is present
rubbing of the skin ... Staphylococcal scalded skin ... #TEN #Dermatology ... #PhysicalExam #Video ... Clinical #SJS #skin
Positive Hoffmann's sign (finger flexor reflex) in a patient with Multiple Sclerosis

The Hoffmann's reflex test itself
Positive Hoffmann's sign ... Hoffmann's reflex test ... are not useful signs ... In cerebellar diseases ... Abnormal #Clinical #Video