11 results
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Initial screening test ... block • Sjogren syndrome ... polymyositis overlap syndrome ... severe disease Treatment ... #management
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Behçet's Syndrome ... occlusion, Budd-Chiari syndrome ... in Behcet syndrome ... adenopathy (PFAPA) syndrome ... hyperimmunoglobulin D syndrome
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... Demyelinating Syndrome ... #CNS #neurology ... #rheumatology # ... cerebritis #diagnosis #management
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
thyroid, Sjogren syndrome ... “dropping head syndrome ... - Kearns-Sayre syndrome ... Eaton myasthenia syndrome ... #neurology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... Periodic fever syndromes ... erythematosus [SLE ... hypersensitivity syndromes ... Macrophage #Activation #Syndrome
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
adults in the west ... microglobulin Treatment ... • Richter’s Syndrome ... leukemia • Sezary syndrome ... Leukemia #diagnosis #workup
Hyponatremia - Diagnosis and Treatment
Hyponatremia is usually caused by the inability to excrete water normally.
Then, ask 3 questions ... to work through ... Treatment: Treatment ... demyelination syndrome ... #management #nephrology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... overlaps with RA, SLE ... • Mikulicz syndrome ... enlargement Sjogren's Syndrome ... #Sjogrens #Syndrome
There are similarities and differences between these 3 conditions which all carry treatment implications. Each mimic
which all carry treatment ... hormones that work ... for Refeeding Syndrome ... #differential #algorithm ... #management #treatment
Posterior Knee Dislocation Injury
Specifically, POSTERIOR KNEE DISLOCATIONS can have significant associated injury that needs unique approach
nerve injury (25%) TEST ... Compartment syndrome ... consider compartment syndrome ... Posterior #Injury #msk ... #clinical #video