63 results
Adrenal Insufficiency Differential Diagnosis Algorithm
Clinical suspicion: Weakness, fatigue, nausea, musculoskeletal pain, dizziness, volume depletion, abdominal pain,
Weakness, fatigue, nausea ... , hypotension, hyponatremia ... , hypoglycemia Testing ... ACTH) stimulation test ... #Algorithm #endocrinology
Hypernatremia Diagnosis and Workup

Step 1 . Repeat the sodium concentration.
Step 2.  Check plasma osmolality.
NORMAL PLASMA
Hypernatremia Diagnosis ... and Workup Step ... hypothyroidism • adrenal insufficiency ... • nephrotic syndrome ... #Diagnosis #Workup
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Causes of Hyponatremia ... - Differential Diagnosis ... Algorithm Syndrome ... • Nephrotic syndrome ... #Algorithm #Causes
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Causes of Hyponatremia ... - Differential Diagnosis ... Algorithm Syndrome ... • Nephrotic syndrome ... #Algorithm #Causes
Adrenal Insufficiency Diagnosis Algorithm
Clinical features: 
 - Weight loss, anorexia, Weakness, fatigue, GI distress
 - Hypotension,
Diagnosis Algorithm ... hypoglycemia, Hyponatremia ... cosyntropin stimulation test ... interact with stim test ... Stimulation #StimTest #Endocrinology
Adrenal Insufficiency - Diagnosis and Management Summary
Primary Adrenal Insufficiency:
Most Common Cause in the US: Autoimmune Adrenalitis
Other
secondary AI, hyponatremia ... hypophysitis, Sheehan's syndrome ... A STIM test can ... ACTH STIM TEST: ... #Management #Endocrinology
Adrenal Insufficiency Diagnosis Algorithm - Evaluation of HPA Axis Response to ACTH

Early am cortisol < 3
Adrenal Insufficiency ... unclear (often the case ... then go to stim testing ... Standard Stim test ... #Endocrinology
Primary Adrenal Insufficiency:
 • ACTH stimulation test - Synthetic ACTH does not stimulate cortisol secretion because
Primary Adrenal Insufficiency ... aldosterone - Low in cases ... Evaluation #laboratory #diagnosis ... #testing #endocrinology ... #workup
Modified Hyponatremia Algorithm
Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants
Hypotonic Hyponatremia: 
 • ADH ON (UOsm > 100):
Modified Hyponatremia ... Cirrhosis, Nephrotic syndrome ... Hypothyroidism, Adrenal insufficiency ... Cerebral salt wasting ... #Algorithm #diagnosis
Hyponatremia - Differential Diagnosis by Mechanism
Decr Blood Pressure (“Decr Effective Circulating Volume”) 
 - Volume depletion
Diagnosis by Mechanism ... - Cirrhosis Syndrome ... Cerebral salt wasting ... Hypothyroidism - Adrenal insufficiency ... #Table #Causes