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diagnosis hematology classification disease hemolysis algorithm elevation endocrinology evaluation glomerular management nephrology nephrotic oncology pathophysiology accuracy acidosis acromegaly adrenal agglutinin
Laboratory Testing in Hemolytic Anemia Intravascular vs Extravascular Hemolysis Reticulocytes Unconjugated bilirubin LDH Peripheral smear Haptoglobin Urine hemosiderin Urine hemoglobin Carboxyhemoglobin #Hemolytic #Anemia #Laboratory #Testing #workup
Laboratory Testing ... in Hemolytic Anemia ... Extravascular Hemolysis ... #Anemia #Laboratory ... #Testing #workup
Hemolysis - Diagnostic Algorithm and Causes Increased red cell production: • Increased Reticulocytosis/polychromasia • Erythroid
Algorithm and Causes ... #Hemolytic #Anemia ... #Algorithm #Differential ... #Causes #Workup ... GrepMed Recommended Text
Anemia - Workup and Differential Diagnosis - History, Physical Exam, Labs - Microcytic - Normocytic -
Anemia - Workup ... and Differential ... Macrocytic - Hemolytic ... #Anemia #Workup ... Diagnosis #causes
Gastrointestinal Evaluation of Iron Deficiency Anemia In patients with anemia, diagnose iron deficiency if: • Ferritin <
Iron Deficiency Anemia ... patients with anemia ... • Additional laboratory ... Non-invasive testing ... Gastrointestinal #Evaluation #workup
Causes of False Elevation and Reduction in HbA1c == False Elevation == Decreased RBC turnover • Iron, B-12,
Causes of False ... • Asplenia Laboratory ... blood loss • Hemolytic ... anemia • Splenomegaly ... Diagnosis #DM2 #Differential
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... #Anemia #Differential ... Diagnosis #Algorithm #workup ... #hematology #testing
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory ... value is low, tests ... anemia Indirect ... WBC count and differential ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Platelet Disorders - Differential ... Diagnosis and Workup ... smear, HIV/HCV testing ... K), H. pylori test ... changes), high MCV anemia
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
anemia • Cold ... Positive Coombs testing ... younger pts) Differential ... • Diagnostic Test ... Donath-Landsteiner test
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Defects: Sickle cell anemia ... Hypophostphatemia Laboratory ... Tests: - Haptoglobin ... #Differential #
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