69 results
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Hypereosinophilic Syndrome ... • Clinically ... suspect underlying hematologic ... Diagnosis and Treatment ... #HES #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... Diagnosis #Algorithm #hematology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... (Clinical Dx). ... is a skin prick test ... , AS Treatment: ... signs #symptoms #rheumatology
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
present both at rest ... improves quickly with rest ... #Joint #Pain #MSK ... #rheumatology # ... approach #workup
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Clinical Presentation ... Liver function tests ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology ... #Rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... Diseases • Septic arthritis ... ANA and RF (if clinical ... #laboratory #workup ... diagnosis #testing #Rheumatology
Telescoping Fingers on Physical Exam

A 69-year-old woman with rheumatoid arthritis presented for the treatment of severe
with rheumatoid arthritis ... presented for the treatment ... RheumatoidArthritis #Clinical ... #Video #Rheumatology
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
Clinical Syndrome ... : • Common Clinical ... vasculitis • Hematologic ... • giant cell arteritis ... Autoinflammatory #Somatic #rheumatology
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
Behcet's Syndrome ... : • Treatment: ... refractory disease Arthritis ... Behcets #disease #Syndrome ... #pharmacology #rheumatology
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
anti-synthetase syndrome ... myositis, and arthritis ... after 2 years of treatment ... Myositis #diagnosis #rheumatology