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diagnosis differential causes transaminitis algorithm lfts acute albumin arterial ascites chemistry elevated embolism gap globulin gradient hypertension interpretation pathophysiology patterns
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... Injury Transaminase ... cirrhosis, Portal Vein Thrombosis ... #Patterns #Liver ... #Injury #hepatology
Elevated Transaminases / Transaminitis - Differential Diagnosis • Infectious: HAV, HCV, HEV, EBV, HSV, CMV •
Trauma: Shock liver ... , Portal vein thrombosis ... • Autoimmune hepatitis ... Transaminases #hepatitis ... Diagnosis #causes #hepatology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Injury - Differential ... • Infectious: Hepatitis ... obstruction, HELLP Syndrome ... #Injury #Differential ... Acute #algorithm #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... vein: Budd-chiari syndrome ... , Thrombosis, Emboli ... #injury #hepatitis ... diagnosis #algorithm #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Check Acute viral hepatitis ... Check Acute viral hepatitis ... Chronic viral hepatitis ... • Gilbert's syndrome ... #differential #Hepatology
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
and hepatorenal syndrome ... Cirrhosis/acute hepatitis ... sarcoidosis) • Liver ... • Portal vein thrombosis ... Diagnosis #causes #hepatology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Venous Thrombosis ... • Nephrotic Syndrome ... , Ischemic Liver ... Vasculitis • Injury ... pathophysiology #hematology
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis High albumin gradient (>1.1 g/dl): - Cirrhosis - Alcoholic
- Alcoholic hepatitis ... ascites - Massive liver ... (Budd-Chiari syndrome ... - Acute fatty liver ... Differential #Diagnosis #hepatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... changes (POEMS syndrome ... Sarcoidosis) • Liver ... gastric tumors • Hematology ... differential #diagnosis #hematology
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