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The Cell Cycle The cell cycle is the series of tightly regulated steps that controls cell growth
The Cell Cycle ... The cell cycle is ... gene (TP53) to ... #cell #cycle #p53 ... Retinoblastoma #tp53
Hobnail variant of PTC: micropapillary architecture, dense eosinophilic cytoplasm, hobnail cells with apical nuclei, and marked
cytoplasm, hobnail cells ... Frequent BRAF V600E, TP53
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
cells can infiltrate ... disease • B cell ... AIHA • Pure red cell ... lymphoma • Hairy cell ... Smoldering adult T cell
Inflammatory mechanism of asthma. Airway epithelial cells exposed to activation stimuli, including allergens, viruses, and irritants,
Airway epithelial cells ... promote dendritic cell ... activate naive CD4 T cells ... These T cells then ... induce B-cell class
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Involvement - B-cell ... CD10 - T-cell ... or λ), Smudge Cells ... - B-cell ... Thrombocytosis - T-cell
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
of ALL is of B-cell ... lymphadenopathy • Blast cells ... organs When Cancer Cells ... Hypogammaglobulinemia, smudge cells ... form of large cell
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
antibodies bind to mast cells ... activation and cell ... with cytotoxic T cells ... natural killer cells ... - Red blood cell
Inflammatory Cascade: Pathogenesis and Clinical Findings Continued Innate Immunity • Phagocytosis: (main mechanism) neutrophils and macrophages engulf
Natural Killer Cells ... • Humoral: (B cell ... : (T cell response ... Increased helper cell ... and cytotoxic cell
Features of a Sickle Cell Crisis Sickle-cell disease - an autosomal recessive blood disorder. Characterized by red
Features of a Sickle Cell ... Crisis Sickle-cell ... These cells can ... leading to a "sickle cell ... Sickle cell disease
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell ( ... transfusion • Target cells ... anemia • Sickle cells ... - Sickle cell anemia ... alcoholism • Burr cells
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