11 results
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
normal volume-based algorithm ... Urine Na+K / serum ... : SIADH, Renal Sodium ... differential #diagnosis #table ... #sodium #nephrology
Hyponatremia Differential Diagnosis Table

 • Step 1: Correct for hyperglycemia. Corrected Na = [(glucose - 100)/
Differential Diagnosis Table ... Corrected Na = [ ... Urine Osm • Na ... Differential #Diagnosis #Table ... #nephrology #sodium
Antiarrhythmics - Sodium Channel Blockers
Subclasses, Mechanisms, Indications, Side Effects
la - Quinidine, Procainamide
lb - Lidocaine, Mexiletine
Ic -
Antiarrhythmics - Sodium ... Antiarrhythmics #Sodium ... Blockers #ClassI #Na ... #pharmacology #table
Diuretic Electrolyte Excretion Effects 
Diuresis, Na+, K+, Mg2+, Ca2+, Cl-, HCO3-, Uric Acid
 - Thiazide Type
Effects Diuresis, Na ... - Epithelial Sodium ... pharmacology #comparison #table
Modified Hyponatremia Algorithm
Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants
Hypotonic Hyponatremia: 
 • ADH ON (UOsm > 100):
Modified Hyponatremia Algorithm ... - RAAS ON (UNa ... - RAAS OFF (UNa ... #Hyponatremia #Algorithm ... #diagnosis #sodium
Causes of Generalized Edema - Differential Diagnosis Algorithm
Overfill (Increased renal sodium retention, Urine Na > 40meq/L)
Differential Diagnosis Algorithm ... Increased renal sodium ... retention, Urine Na ... Differential #Diagnosis #Algorithm
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
Renal glucosuria - Na ... Bartter syndrome - Na-K ... cell epithelial sodium ... of epithelial sodium ... #Differential #Table
Volume Based Approach to Hyponatremia
Hypovolemic, Serum uric acid >4
 • Urine Na <20: Extra-renal losses
 •
acid >4 • Urine Na ... losses • Urine Na ... acid >4 • Urine Na ... #Hyponatremia #algorithm ... #diagnosis #sodium
Management of Hyponatremia
Hypertonic Saline - Only indicated if patient has severe symptoms + Na < 125
Give
severe symptoms + Na ... correction rate for Na ... • Check Na levels ... Hyponatremia #Management #algorithm ... #treatment #sodium
Refractory Ascites - Ascites that cannot be mobilized or early recurrence that cannot be prevented
Diuretic Resistant:
response to dietary Na ... despite dietary sodium ... days, Urinary sodium ... >2.0 mg/dL • Na ... diagnosis #management #algorithm