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diagnosis differential algorithm management liver causes injury acute chronic lfts rheumatology syndrome aclf aih antibodies antivirals associations autoantibodies cll coagulation
Here is a quick guide on the common direct-acting antivirals (DAAs) for chronic hepatitis C virus
DAAs) for chronic hepatitis ... DAAs #Antivirals #table ... #treatment #hcv ... #medications #infectiousdisease ... #hepatology #HepC
Common Etiologies of Cirrhosis Inflammation - Hepatitis B (15 percent) - Hepatitis C (47 percent) - Schistosomiasis
Etiologies of Cirrhosis ... Inflammation - Hepatitis ... 15 percent) - Hepatitis ... Schistosomiasis - Autoimmune ... #Differential #Hepatology
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 Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
Hemochromatosis • Wilson's Disease ... • Autoimmune ... Hepatitis • Drug ... Primary Biliary Cirrhosis ... Algorithm #Causes #Hepatology
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
Anticoagulant Medications ... Alcohol, Viral hepatitis ... , Autoimmune • ... Deficiencies #Summary #table ... comparison #diagnosis #hematology
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
common in SLE, autoimmune ... hepatitis Anti-CCP ... Primary biliary cirrhosis ... #diagnosis #table ... #rheumatology #
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Toxic: Alcohol, Medication ... Other: NAFLD, Autoimmune ... Syndrome, Celiac Disease ... GVHD • Toxic: Medication ... Acute #algorithm #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
those with CLD (± cirrhosis ... months without treatment ... underlying liver disease ... (DILI) Viral Hepatitis ... #Hepatology #gastroenterology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
• Ischemia • Autoimmune ... • Cholestatic disease ... • Alcoholic hepatitis ... Infiltrative • Cirrhosis ... Others #LFTs #Hepatology
Hepatitis B - Treatment Indications Treatment not indicated: • Immune tolerant state - HBe-Ag detectable, high HBV
Hepatitis B - Treatment ... Indications Treatment ... Family history of cirrhosis ... or fibrosis • Cirrhosis ... #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
• Infections: Hepatitis ... , HSV, VZV • Medications ... Other: NAFLD, Autoimmune ... HELLP, Celiac disease ... Differential #Diagnosis #hepatology
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