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diagnosis classification comparison druginduced hypersensitivity management reactions sle systemic types activation ana antinuclear autoantibodies differential hematology macrophage mas medications pathophysiology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... Erythematosus ( ... Evolution: Chronic disease ... sle #comparison #table ... #rheumatology #
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
allergies, and drug ... during hemolytic disease ... , and systemic lupus ... erythematosus ... Diagnosis #Reactions #Table
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Association with disease ... SLE (60-70%) & drug-induced ... #erythematosus ... #diagnosis #rheumatology ... #table #ANA
Drug Induced Systemic Lupus Erythematosus > 100 drugs have been associated with drug-induced SLE High risk (>5%): •
Lupus Erythematosus ... for 1 year of treatment ... #Erythematosus ... #pharmacology # ... differential #diagnosis #rheumatology
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Summary table of ... Food allergies, Drug ... reaction, Haemolytic disease ... glomerulonephritis, Systemic lupus ... erythematosus Type
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
• Systemic lupus ... erythematosus ... ) • Sepsis • Drug-induced ... Treatment: • Corticosteroids ... #Rheumatology
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