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hematology management chronic cll differential hemeonc leukemia lymphocytic anemia aplastic causes classification diffuse disorders emergencies eosinophil eosinophilia hodgkins lad lymphadenopathy
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Diagnosis: • ... microglobulin Treatment ... Lymphocytic #Leukemia #diagnosis ... #workup #oncology ... #hematology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
- Differential Diagnosis ... Algorithm Reactive ... Lymphocytic Leukemia (CBC ... Reed-Sternberg Cells ... #Hematology #Oncology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Disorders Testing Algorithm ... evaluation or workup ... /µL Workup • Screen ... glucocorticoid treatment ... #Differential #diagnosis
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
minimal tumor burden Diagnosis ... lymphocytes, smudge cells ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc ... #diagnosis #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... factor (GCSF) treatments ... Workup: • Complete ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Marrow (Toxic injury ... number of CD34+ cells ... aplastic anemia Treatment ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma Workup ... lymph node biopsy (diagnostic ... Hodgkin Lymphoma Treatment ... Hodgkins #lymphoma #diagnosis ... #oncology #management
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
full infectious work-up ... days → add fungal work-up ... interventional radiology ... “big & sticky” cells ... #HemeOnc #Diagnosis
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
• CBC + diff • ... Bone marrow Treatment ... #Plasmacytoma #Oncology ... #Diagnosis #Workup ... #Hematology
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