9 results
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... - CHAMPS Mnemonic ... subacute bacterial endocarditis ... Hypocomplementemia #Low #Complement ... #diagnosis #differential
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
pathophysiologic causes ... staining): • Low Complement ... Cryoglobulinemia, Endocarditis ... Pauci-immune mediated (Negative ... #differential #diagnosis
My Patient with Infective Endocarditis (IE) Has Negative Blood Cultures
 - Did they receive antibiotics prior
with Infective Endocarditis ... Decreased yield due ... therapy - Number one cause ... #Infective #Endocarditis ... #Diagnosis #Management
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
• Coagulase-negative ... Septic Emboli Cause ... Diagnosis? ... Suspicion -> TEE • Duke ... Substance use: R > L Tricuspid
CREAM Mnemonic for Causes of Aortic Regurgitation

C - Congenital (Bicuspid Aortic Valve)
R - Rheumatic disease -
CREAM Mnemonic for ... Causes of Aortic ... - Congenital (Bicuspid ... endemic areas E - Endocarditis ... #Differential #Diagnosis
Blood Culture-Negative Infective Endocarditis (BCNIE)
Definition: No etiology found after 3 separate blood cultures remain negative for
Infective Endocarditis ... " BCNIE may be due ... but important causes ... BCNIE Diagnostic ... #Infective #Endocarditis
Endocarditis - Overview and Differential Diagnosis Framework

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV
aureus, Coagulase-negative ... staphylococci Culture Negative ... Septic emboli cause ... Suspicion → TEE • Duke ... substance use: R > L Tricuspid
Capnocytophaga Canimorsus Skin Rash

40 M presents w/ N, V, severe epigastric pain. SHx: smoker, drinks 18
dogs & latter can cause ... bacillus cause ... to meningitis, endocarditis ... gangrene. sepsis due ... the key to the diagnosis
SEPSIS AND SEPTIC SHOCK

DEFINITION AND PATHOPHYSIOLOGY
 • Sepsis: Life-threatening organ dysfunction due to a dysregulated host
organ dysfunction due ... NETs), cytokines, complement ... Gram-positive/-negative ... mental status DIAGNOSIS ... Septic #Shock #Diagnosis