22 results
Summary of the adverse effects associated with the use of trimethoprim–sulfamethoxazole

Mnemonic - NOT RISKY?

N - Neurologic
with the use of trimethoprim–sulfamethoxazole ... TMPSMX #bactrim #trimethoprim
Folate Deficiency - Causes of Decreased Folic Acid
↓ Intake: Diet, Age, Alcohol
↑ Demand: Pregnancy, Infancy, Hemolysis,
Sulfasalazine, Trimethoprim
Drugs causing hyperkalemia
 • Impaired release of renin: NSAIDs, Beta blockers, Cyclosporine, tacrolimus, Diabetes, Elderly
 •
: Triamterene, Trimethoprim
Etiologies of Hypoaldosteronism

Hyporeninemic Hypoaldosteronism (Low Renin, Low Aldosterone)
 - Diabetic Nephropathy 
 - NSAIDs
Non-Hyporeninemic Hypoaldosteronism (Normal
antagonists - Trimethoprim
Pneumocystis jirovecii Pneumonia 
Clinical 
 • Caused by Pneumocystis jirovecii (formerly carinil) 
 • Immunocompromised host
gradient > 35 • Trimethoprim-sulfamethoxazole
Classification of Some Antimicrobial Agents by Their Sites of Action
Inhibitors of metabolism: Sulfonamides, Trimethoprim
Inhibitors of cell
Sulfonamides, Trimethoprim
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
, Triamterene, Trimethoprim
The Diagnostic Approach to Hyperkalemia
Drugs
 - Amiloride
 - Spironolactone
 - Triamterene
 - Trimethoprim
 - Pentamidine
 -
Triamterene - Trimethoprim
Antibiotics - Mechanisms and Sites of Action 

Inhibit Cell Wall Synthesis or Function 
- Beta Lactams,
Folate Synthesis: Trimethoprim
HYPOGLYCEMIA IN NON-DIABETICS:

•	Hormonal dysfunction
Levofloxacin, trimethoprim-sulfamethoxazole