10 results
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Overall Approach ... Normochromic RBCs on Smear ... Spherocytes on Smear ... Diagnosis #Algorithm #Causes ... #Hematology
Leukoerythroblastosis and myelophthisic anemia can be associated with any marrow-replacing process. In this case, the likely
myelophthisic anemia ... In this case, the ... Leukoerythroblastosis #Hematology ... #Pathology #Smear
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Approach to Thrombocytosis ... Peripheral Smear ... for workup, including ... hemolysis, deficiency anemia ... Inflammatory Conditions: Rheumatologic
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... peripheral blood smear ... changes), high MCV anemia ... dysplasia on the smear ... #Workup #hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
Framework for Anemia ... (Morphological Approach ... of chronic kidney ... differential #diagnosis #causes ... #hematology
Simplified Approach to Acute Kidney Injury (AKI)
1) IS THIS AN EMERGENCY? 
Is there a dialysis indication
Simplified Approach ... to Acute Kidney ... e.g AEIOU ) or anuria ... are caused by prerenal ... KidneyInjury #simplified #workup
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
result in severe anemia ... Peripheral blood smear ... immune hemolytic anemia ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup ... #Hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... formed or don’t work ... Peripheral Smear ... Workup: • Complete ... Peripheral blood smear
Scleroderma Renal Crisis (SRC)

Clinical Presentation of Scleroderma Renal Crisis:
1) Acute kidney injury
2) Abrupt onset of hypertension
3)
Crisis: 1) Acute kidney ... microangiopathic hemolytic anemia ... rule out other pathology ... • Refractory cases ... Renal #Crisis #rheumatology
Solitary Cell Plasmacytoma

What?
• Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma)
• In 3%
• No CRAB - no anemia ... hypercalcemia, or kidney ... IFE, FLC assay Pathology ... Oncology #Diagnosis #Workup ... #Hematology