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management oncology rheumatology causes chronic cll leukemia lupus lymphocytic renal algorithm ckd classification coagulation comparison crisis damage dermatology dic differential
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... • Peripheral smear ... microglobulin Treatment ... #workup #oncology ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
minimal tumor burden Diagnosis ... • Peripheral smear ... immunophenotype Clinical ... Leukemia #oncology #hematology ... #hemeonc #diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Peripheral Smear ... Workup: • Complete ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
Related Disease Clinical ... lesions, meninges, kidneys ... increased IgG4+ cells ... management #phenotypes #workup ... #treatment #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... myalgia, serositis, Kidney ... • Immunologic Workup ... Lupusreference #druginduced ... #diagnosis #management
Monoclonal Gammopathy of Renal Significance (MGRS) MGRS • MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
Clinical Clues: ... light-chain ratio Diagnostic ... Workup: • Kidney ... microangiopathy Treatment ... #Significance #Diagnosis
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
organ damage Clinical ... • Peripheral smear ... Schistocytes, helmet cells ... #Coagulation #diagnosis ... #management #hematology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
- Differential Diagnosis ... Dermatomyositis Clinical ... nephrotoxicity to kidney ... tubular cells ... #nephrology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... Hodgkin Lymphoma Workup ... lymph node biopsy (diagnostic ... Hodgkin Lymphoma Treatment ... classification #hematology
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
to 1:1 F:M • Clinical ... myalgia, serositis, Kidney ... • Immunologic Workup ... Lupusreference #DrugInduced ... #diagnosis #treatment
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