15 results
Approach to Headaches - Differential Diagnosis Algorithm

Red flags (PHANTOMS):
 • Pattern change, progressively worse, papilledema
 •
- Differential ... papilledema • Horner syndrome ... history of cancer, HIV ... Space-occupying brain ... lesionCNS
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent
Multiple Ring-Enhancing Lesions:
 • Toxoplasmosis (CD4 < 100)
 • Other
CNS Ring-Enhancing ... Diagnosis- Compatible syndrome ... lung nodules, may also ... #Brain #differential ... causes #radiology #neurology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
HIV / AIDS - Differential ... Symptoms: Fever, headache ... Symptoms: Fever, headache ... #differential # ... InfectiousDiseases #Neurology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
symptoms (headache ... Medium and large also ... Behcet disease) Differential ... Reactive Arthritis, AS ... #diagnosis #management
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
bilateral white matter lesions ... well-defined than PML lesions ... The clinical syndrome ... reversible • HAND is also ... dementia #AIDS #Neurology
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
affecting the Brain ... is important, as ... pachymeningitis • HIV ... LHON) plus MRI lesions ... #differential #
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... , Headache, Movement ... thrombosis and/or blood-brain ... (for secondary APS ... cerebritis #diagnosis #management
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Weakness - Differential ... pulmonary etc) • CNS ... nervous system: Brain ... • Infectious: Brain ... parainfluenza, Coxsackie, HIV
Neurological Manifestations of Tuberculosis
Spinal Arachnoiditis & Polyradiculopathy:
 • Subacute onset of limb weakness, bladder/bowel dysfunction, muscle
Reconstitution Inflammatory Syndrome ... (IRIS): • In HIV ... contrast enhancement Brain ... Tuberculosis #diagnosis #differential ... #TB #neurology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
characterized by: • Headache ... showing cortical lesions ... Reversible course Differential ... #diagnosis #management ... #neurology