16 results
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
Tests - AST, ALT, Alkaline ... Alkaline phosphatase ... AlkPhos #Bilirubin #Hepatology ... #Pathophysiology ... #Diagnosis #LFTs
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
synthesized in: liver ... Most cases diagnosed ... deficiency • blood ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... = nonspecific (nausea ... , vomiting, abdominal ... ) Differential Diagnosis ... #Pregnancy #hepatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... plateletcount), peripheral blood ... : INR/PT, aPTT(liver ... Refractory ITP, ... #hematology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... intralobular bile ducts causes ... PBC Labs: • Alkaline ... or higher • Liver ... #workup #hepatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
ABO incompatible blood ... protein C and S Pathophysiology ... • TMA’s (HUS/TTP ... DIC • Severe Liver ... #Coagulation #diagnosis
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
- Differential Diagnosis ... Hyperviscosity, TTP ... Syndrome, Ischemic Liver ... coagulation and other causes ... Venous #Arterial #pathophysiology
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
the setting of liver ... lung disease Caused ... passage • Arterial blood ... contrast-enhanced TTE ... management #treatment #hepatology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Transfusion Purpura (PTP ... Causes purpura & ... eruptions, diarrhea, liver ... #Transfusions #diagnosis ... #management #hematology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Transfusion Purpura (PTP ... Causes purpura & ... eruptions, diarrhea, liver ... #Transfusion #diagnosis ... #management #hematology