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diagnosis differential management workup cirrhosis hepatopulmonary product reactions syndrome transfusion treatment abscess aflp air algorithm alkaline alkphos alp arterial ascites
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism AST and ALT: • AST: liver
Liver Chemistry ... Phosphatase and Bilirubin ... initial insult Bilirubin ... bile canaliculi (ATP-dependent ... #Hepatology #Pathophysiology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Fragmentation - MAHA: TTP ... Defects, Drugs, Liver ... - Peripheral Blood ... - Unconjugated Bilirubin ... Differential #Diagnosis #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
plateletcount), peripheral blood ... : INR/PT, aPTT(liver ... bypass), LFT (liver ... Refractory ITP, ... #Workup #hematology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... = nonspecific (nausea ... , vomiting, abdominal ... #Pregnancy #hepatology ... diagnosis #management #pathophysiology
Ascites - Diagnostic Approach and Differential Diagnosis The most common causes: cirrhosis, malignancy and heart failure. Approx
The most common causes ... more than one cause ... auscultatory percussion, abdominal ... brown: elevated bilirubin ... Differential #Diagnosis #hepatology
Inherited Non-hemolytic Disorders of Hyperbilirubinemia == Disorders of Conjugation == Gilbert Syndrome: • 5-10% of the population
of hemolysis or liver ... symptoms, such as abdominal ... and stress may cause ... in the blood ... #hepatology #diagnosis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Algorithm Vascular Causes ... week • Direct bilirubin ... Elevation: • Bilirubin ... intestines, white blood ... diagnosis #algorithm #hepatology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory ... of Peripheral blood ... anemia Indirect bilirubin ... impairment #TTP ... Diagnosis #Workup #Hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
ABO incompatible blood ... protein C and S Pathophysiology ... • TMA’s (HUS/TTP ... DIC • Severe Liver ... treatment #management #hematology
Portal venous gas on hepatic ultrasound: A concerning finding in the critically ill patient that should
ileus), intra-abdominal ... variety of other causes ... venousgas #ultrasound #hepatology ... #liver #pocus #
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