17 results
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Diagnosis Framework ... Fragmentation - MAHA: TTP ... Autoimmune: Warm AIHA, Cold ... Laboratory Tests ... #Diagnosis #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Viral Infection Clinical ... younger pts) Differential ... Test: Donath-Landsteiner ... test #cold # ... hemolytic #anemia #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... thrombocytopenic purpura (TTP ... ) (e.g. lupus, CLL ... Extravascular #Causes #differential ... #diagnosis #hematology
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
life Causes and clinical ... Disorientation, vertigo Diagnostic ... tests - Ice cube ... test, TempTest ... #diagnosis #rheumatology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
west • M > F ... Orange or Hep C Clinical ... Diagnosis: • ... aplasia • ITP ... workup #oncology #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... practices that could ... K), H. pylori test ... not required in all ... Refractory ITP,
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
box indicates all ... the tests that ... Abnormal #Algorithm #Hepatology ... Liver #Enzymes #Differential ... #Diagnosis
Ulcerative Blastomycosis Skin Lesion
57 asymptomatic M from Indiana nonpruritic, painless, progressive skin lesion lower back x
Lives in an old ... Diagnosis? ... heaped up borders); differential ... Blastomycosis #SkinRash #dermatology ... #clinical #photo
Acute Dacryocystitis- A 4-week-old boy was brought to the emergency department after having drainage from both
The white-cell count ... He received a diagnosis ... orbital cellulitis ... #NEJM #clinical ... #photo #peds #acute
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Lymphoma (HCV) • CLL ... cold IgG • Lupus ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology