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leukemia management chronic hemeonc lymphocytic workup algorithm cancer cell classification differential differentiation emergencies hodgkins infections infectiousdiseases lymphoma mds mycobacteria myelodysplasia
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, CML, AML, APML ... marrow leading to ... Fibrinolysis & DIC • Tumor ... #Leukemia #Hematology ... #Oncology #Diagnosis
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome in APML ... Triggers: ATRA treatment ... • Induce blast cell ... Imaging: CXR- pulmonary ... #hematology #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Diagnosis: • ... microglobulin Treatment ... DLBCL, PML leukemia ... #workup #oncology ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Lymphocytic Leukemia (CLL ... patients with minimal tumor ... burden Diagnosis ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
antibiotics TLS (tumor-lysis ... syndrome): - Hematologic ... ± tocilizumab; call ... renal failure, pulmonary ... #HemeOnc #Diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
factor (GCSF) treatments ... marrow studies Treatment ... Immunosuppressive treatment ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... (Inflammatory marker ... Hodgkin Lymphoma Treatment ... classification #hematology ... #oncology #management
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Kansasii: • Mimics TB ... Advanced HIV (CD4 cell ... Hematologic malignancy ... including therapy with tumor ... Diagnosis Of NTM
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
syndromes current treatment ... median age at diagnosis ... cardiovascular or pulmonary ... with repeated red cell ... #algorithm #hematology
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
body with 80% to ... X-Ray Imaging: • Marked ... Bone marrow Treatment ... #Plasmacytoma #Oncology ... #Hematology
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