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diagnosis differential clinical management algorithm causes nephrology physicalexam neurology video cardiology treatment pathophysiology radiology table comparison microscopy signs symptoms hematology
Nephritic vs Nephrotic Syndrome Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes. Step
Nephritic vs Nephrotic Syndrome ... nephrotic/nephritic syndromes ... hematuria (RBC casts ... dysmorphic RBCs in urine ... Nephritic #Nephrotic #Syndrome
Glomerular Diseases - Nephritic and Nephrotic Syndromes Nephritic syndrome—due to GBM disruption. Hypertension. t BUN and creatinine.
and Nephrotic Syndromes ... Nephritic syndrome—due ... RBC casts in urine ... but in severe cases ... Nephritic #Nephrotic #Syndromes
Urinary Casts and Disease Associations Hyaline - May be nonspecific; seen in normal individuals or during severe
Urinary Casts and ... and concentrated urine ... breakdown of cellular casts ... heme-granular casts ... Fatty - Nephrotic syndrome
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Proteinuria (Negative urine ... • Fanconi's syndrome ... Proteinuria (Positive urine ... albuminuria) - Active urine ... sediment - WBC/RBC casts
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
1ml blood/liter urine ... disease - Alport syndrome ... pain hematuria syndrome ... hematuria: - RBC casts ... • Nutcracker syndrome
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
GN • Active Urine ... dysmorphic RBC, RBC casts ... anti-phospholipid syndrome
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
hemolytic-uremic syndrome ... arbitrarily defined as urine ... cell/white cell casts ... because nephritic urine ... proteinuria #nephrotic #syndrome
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
iniury, Compartment syndrome ... Neuroleptic malignant syndrome ... Cast formation: ... hour with goal urine
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
- Compartment syndrome ... Weakness - Dark urine ... or compartment syndrome ... Cast formation: ... hour with goal urine
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Pulmonary Renal Syndromes ... Pulmonary Renal Syndromes ... Anti-GBM antibody • Urine ... : UA, Urine protein ... hematuria, RBC casts
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