1790 results
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Autoantibodies to vWF ... thrombocythemia), Autoimmune disease ... • vWF adsorption
Factor VIII synthesis - Normal, Haemophilia A and Von Willebrand Disease

Normal - vWF carrier protein protects
Von Willebrand Disease ... Normal - vWF ... Von Willebrand Disease ... the absence of vWF ... VonWillebrand #Disease
Von Willebrand Disease Classification
Type 1 (Accounts for ~3/4 of cases):
 • Defect: Quantitative defect (i.e. not
Von Willebrand Disease ... i.e. not enough VWF ... dysfunctional VWF ... total absence of vWF ... VonWillebrand #Disease
Platelet disorders and Aggregometry
Glanzmann Thrombasthenia
 • Defective aggregation to all agonists except ristocetin
 • Normal platelet,
also be seen in vWD ... differentiate vWD ... BS by measuring vWF ... Von Willebrand Disease
Approach to Von Willebrand disease (VWD)

By Matthew Ho, MD PhD @MatthewHoMD

#VWD #Von #Willebrand #VonWillebrand #disease #hematology
Von Willebrand disease ... (VWD) By Matthew ... MatthewHoMD #VWD ... VonWillebrand #disease
Bleeding manifestations 
Petechiae are small, flat, red, discrete areas of skin bleeding that are typically <2
Diagnosis VWF ... (Quantity of VWF ... considered to be low) VWF ... of this plasma VWF ... (differentiate VWD
Coagulation cascade and anticoagulants 

Satyendra Dhar MD, @DharSaty

#coagulation #coumadin #heparin #warfarin #apaxiban #pradaxa #xarelto #DOAC #vWF
xarelto #DOAC #vWF
General overview of lung diseases. 

#diagnosis #causes #lung #disease #restrictive #obstructive #pulmonary #respiratory #pearls #ddxof
overview of lung diseases ... #causes #lung #disease
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome:
 - Acute poststreptococcal 
glomerulonephritis 
 - Rapidly progressive
Glomerular Diseases ... glomerulonephritis - Berger disease ... Minimal change disease ... #Glomerular #Diseases
Eosinophils (Eos) and hypereosinophilia (HE)
Caused by eosinophilopoietic cytokines
Common causes:
 - Drug reaction
 - Helminth infection
 -
reaction - Atopic disease ... lymphomas, Hodgkin disease ... Chronic inflammatory diseases ... , IgG4-related disease ... inflammatory bowel diseases