29 results
Systemic Lupus Erythematosus: Gastrointestinal Manifestations
 - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Systemic Lupus Erythematosus ... the pancreas, Vasculitis ... Complications #pathophysiology ... #signs #symptoms ... #diagnosis
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
• Myopathy (Also ... Erythematosus #SLE #MSK ... Complications #pathophysiology ... #signs #symptoms ... #diagnosis
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... Livedo Reticularis, Vasculitis ... Manifestations #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
inflammation Others: • Lupus ... aneurysms can also ... systemic lupus ... Presentation - Systemic Symptoms ... purpura: strong sign
Kawasaki Disease: Clinical Findings
Diagnostic Criteria - Fever and 4/5 of the following:
 • Conjunctivitis
 • Polymorphous
Clinical Findings Diagnostic ... Criteria - Fever ... #Diagnosis #Pathophysiology ... #Signs #Symptoms ... #Vasculitis
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Dehydration • Symptoms ... WBC >100k, + lab signs ... Lysis Syndrome: • Pathophysiology ... #diagnosis #management
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
syndromes such as ... Signs and symptoms ... criteria for MS ... Multiple Sclerosis Treatment ... management #neurology #treatment
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
Polycythemia Vera (PV) - Diagnosis ... Management Summary Diagnostic ... Criteria: • Elevated ... When present, symptoms ... , signs, and complications
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear

Visual or auditory symptoms in conjunction
is important, as ... early diagnosis ... and treatment can ... syndrome • Systemic lupus ... ANCA-associated vasculitides
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
lumbar spine Signs ... CaudaEquina #Syndrome #MSK ... #pathophysiology ... #diagnosis #symptoms ... #signs